730 research outputs found

    Towards Learning ‘Self’ and Emotional Knowledge in Social and Cultural Human-Agent Interactions

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    Original article can be found at: http://www.igi-global.com/articles/details.asp?ID=35052 Copyright IGI. Posted by permission of the publisher.This article presents research towards the development of a virtual learning environment (VLE) inhabited by intelligent virtual agents (IVAs) and modeling a scenario of inter-cultural interactions. The ultimate aim of this VLE is to allow users to reflect upon and learn about intercultural communication and collaboration. Rather than predefining the interactions among the virtual agents and scripting the possible interactions afforded by this environment, we pursue a bottomup approach whereby inter-cultural communication emerges from interactions with and among autonomous agents and the user(s). The intelligent virtual agents that are inhabiting this environment are expected to be able to broaden their knowledge about the world and other agents, which may be of different cultural backgrounds, through interactions. This work is part of a collaborative effort within a European research project called eCIRCUS. Specifically, this article focuses on our continuing research concerned with emotional knowledge learning in autobiographic social agents.Peer reviewe

    On Writ of Certiorari to the United States Court of Appeals for the Ninth Circuit, Brief of Product Liability Advisory Council, Inc., National Association of Manufacturers, Business Roundtable, and Chemical Manufacturers Association as Amici Curiae in Support of Respondent, William Daubert and Joyce Daubert, Individually and as Guardians Ad Litem for Jason Daubert, and Anita De Young, Individually and as Gaurdian Ad Litem for Eric Schuller v. Merrell Dow Pharmaceuticals, Inc.

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    The Federal Rules of Evidence exclude expert scientific testimony when it has been developed without regard for accepted scientific methods. This case focuses on expert scientific evidence. Such evidence plays a vital and often dispositive role in modern litigation. For scientific evidence to be helpful to the factfinder it must meet some minimal threshold of reliability. To hold otherwise would be to allow a system of adjudication based more on chance than on reason

    Test Items in the Complete and Short Forms of the BOT-2 that Contribute Substantially to Motor Performance Assessments in Typically Developing Children 6-10 Years of Age

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    Objectives: Determine the magnitude of association between individual subtest items of the Bruininks-Oseretsky Test of Motor Proficiency, second edition (BOT-2), and the respective total subtest scores and to review items on the BOT-2 Short Form. Background: The Bruininks-Oseretsky Test of Motor Proficiency, second edition (BOT-2), is a test used to measure gross motor proficiency in both typically developing children and children with developmental disabilities between the ages of four and twenty-one. The BOT-2 Short Form consists of fourteen test items proportionally selected from the subtests of the Complete Form. It can be used as a screening tool and takes less time to administer. Methods and Measures: A convenience sample of forty-four children (twenty-one male, twenty-three Female; six to ten years), who were enrolled at a Midwestern elementary school, participated. Data was collected in one session. The BOT-2 subtests of Manual Dexterity, Bilateral Coordination, Running Speed and Agility, and Upper Limb Coordination were administered to subjects. Subjects progressed through the subtests in random order and each subtest was graded and administered by a consistent person. Means and standard deviations were calculated for the scores on the individual subtest items. Pearson correlation tests were run to determine the magnitude of the association between the individual subtest items and the respective subtest total score; the magnitude of association was assessed to see if the items that make up the Short Form were strongly associated with their subtest total score. Results: All items in the Manual Dexterity, Running Speed and Agility, and Upper Limb Coordination subtest were significantly correlated (p \u3c 0.05) with their overall subtest score. Two items in the Bilateral Coordination subtest were not significantly correlated with the overall subtest score, one that was included on the Short Form. Conclusions: Most items on the BOT-2 subtests administered were significantly correlated with their overall respective subtest scores. However, revisions to the short form may be needed in order to include more items that are all significantly correlated with their respective subtest scores

    Unusual Loop-Sequence Flexibility of the Proximal RNA Replication Element in EMCV

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    Picornaviruses contain stable RNA structures at the 5′ and 3′ ends of the RNA genome, OriL and OriR involved in viral RNA replication. The OriL RNA element found at the 5′ end of the enterovirus genome folds into a cloverleaf-like configuration. In vivo SELEX experiments revealed that functioning of the poliovirus cloverleaf depends on a specific structure in this RNA element. Little is known about the OriL of cardioviruses. Here, we investigated structural aspects and requirements of the apical loop of proximal stem-loop SL-A of mengovirus, a strain of EMCV. Using NMR spectroscopy, we showed that the mengovirus SL-A apical loop consists of an octaloop. In vivo SELEX experiments demonstrated that a large number of random sequences are tolerated in the apical octaloop that support virus replication. Mutants in which the SL-A loop size and the length of the upper part of the stem were varied showed that both stem-length and stability of the octaloop are important determinants for viral RNA replication and virus reproduction. Together, these data show that stem-loop A plays an important role in virus replication. The high degree of sequence flexibility and the lack of selective pressure on the octaloop argue against a role in sequence specific RNA-protein or RNA-RNA interactions in which octaloop nucleotides are involved

    Test Items in the Complete and Short Forms of the BOT-2 that Correlate to Subtest Score in Typically Developing Children 6-10 Years of Age

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    The Bruininks-Oseretsky Test of Motor Proficiency, second edition (BOT-2), is used to measure fine and gross motor proficiency in children ages 4- 21 years.1 The BOT-2 consists of both a Complete and Short Form and is comprised of 4 composites with 8 subtests. The Short Form consists of 14 items proportionally selected from the subtests of the Complete Form. Despite requiring less time to administer and score, a group of researchers found that the BOT-2 Short Form is not a valid measure for assessing motor proficiency in 4-6 year olds, suggesting that a revision of the Short Form may be advised.2 Brahler et al3 investigated 4 subtests (Strength, Balance, Precision and Integration) with children 6-10 years of age. They found that several items were poorly associated with their subtest total scores and the Short Form contained low yield items in 3 of these subtests.https://ecommons.udayton.edu/dpt_symposium/1010/thumbnail.jp

    Assessment of the potential in vivo ecotoxicity of Double-Walled Carbon Nanotubes (DWNTs) in water, using the amphibian Ambystoma mexicanum

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    Because of their specific properties (mechanical, electrical, etc), carbon nanotubes (CNTs) are being assessed for inclusion in many manufactured products. Due to their massive production and number of potential applications, the impact of CNTs on the environment must be taken into consideration. The present investigation evaluates the ecotoxic potential of CNTs in the amphibian larvae (Ambystoma mexicanum). Acute toxicity and genotoxicity were analysed after 12 days of exposure in laboratory conditions. The genotoxic effects were analysed by scoring the micronucleated erythrocytes in the circulating blood of the larvae according to the French standard micronucleus assay. The results obtained in the present study demonstrated that CNTs are neither acutely toxic nor genotoxic to larvae whatever the CNTs concentration in the water, although black masses of CNTs were observed inside the gut. In the increasing economical context of CNTs, complementary studies must be undertaken, especially including mechanistic and environmental investigations

    Lowering IceCube's energy threshold for point source searches in the Southern Sky

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    Observation of a point source of astrophysical neutrinos would be a "smoking gun" signature of a cosmic-ray accelerator. While IceCube has recently discovered a diffuse flux of astrophysical neutrinos, no localized point source has been observed. Previous IceCube searches for point sources in the southern sky were restricted by either an energy threshold above a few hundred TeV or poor neutrino angular resolution. Here we present a search for southern sky point sources with greatly improved sensitivities to neutrinos with energies below 100 TeV. By selecting charged-current ν μ interacting inside the detector, we reduce the atmospheric background while retaining efficiency for astrophysical neutrino-induced events reconstructed with sub-degree angular resolution. The new event sample covers three years of detector data and leads to a factor of 10 improvement in sensitivity to point sources emitting below 100 TeV in the southern sky. No statistically significant evidence of point sources was found, and upper limits are set on neutrino emission from individual sources. A posteriori analysis of the highest-energy (~100 TeV) starting event in the sample found that this event alone represents a 2.8σ deviation from the hypothesis that the data consists only of atmospheric background.Fil: Aartsen, M. G.. University of Adelaide; AustraliaFil: Abraham, K.. Technische Universität München; AlemaniaFil: Ackermann, M.. Deutsches Elektronen-Synchrotron; AlemaniaFil: Adams, J.. University Of Canterbury; Nueva ZelandaFil: Aguilar, J. A.. Université Libre de Bruxelles; BélgicaFil: Golup, Geraldina Tamara. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; ArgentinaFil: Wallace, A.. University of Adelaide; AustraliaFil: Wallraff, M.. Rwth Aachen University; AlemaniaFil: Wandkowsky, N.. University of Wisconsin; Estados UnidosFil: Weaver, Ch.. University of Alberta; CanadáFil: Wendt, C.. University of Wisconsin; Estados UnidosFil: Westerhoff, S.. University of Wisconsin; Estados UnidosFil: Whelan, B. J.. University of Adelaide; AustraliaFil: Whitehorn, N.. University of California at Berkeley; Estados UnidosFil: Wickmann, S.. Rwth Aachen University; AlemaniaFil: Wiebe, K.. Johannes Gutenberg Universitat Mainz; AlemaniaFil: Wiebusch, C. H.. Rwth Aachen University; AlemaniaFil: Wille, L.. University of Wisconsin; Estados UnidosFil: Williams, D. R.. University of Alabama at Birmingahm; Estados UnidosFil: Wills, L.. Drexel University; Estados UnidosFil: Wissing, H.. University of Maryland; Estados UnidosFil: Wolf, M.. Stockholms Universitet; SueciaFil: Wood, T. R.. University of Alberta; CanadáFil: Woschnagg, K.. University of California at Berkeley; Estados UnidosFil: Xu, D. L.. University of Wisconsin; Estados UnidosFil: Xu, X. W.. Southern University; Estados UnidosFil: Xu, Y.. Stony Brook University; Estados UnidosFil: Yanez, J. P.. Deutsches Elektronen-Synchrotron; AlemaniaFil: Yodh, G.. University of California at Irvine; Estados UnidosFil: Yoshida, S.. Chiba University; JapónFil: Zoll, M.. Stockholms Universitet; Sueci
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